博士,华中科技大学药理学系。
研究方向:药物递送系统,模式动物,药代动力学、药效学及药物毒理学的研究。
电话:13377890467
邮箱:2018220193@hust.edu.cn
地址:武汉市航空路13号药学院1号楼609室
教育与工作经历
2006/9-2011/6,安徽医科大学,临床药理学,学士,
2011/9-2016/6,华中科技大学,药物化学,博士
2016/7-2018/7,华中科技大学,博士后
2018/7-至今,华中科技大学,讲师
主持科研项目
国家自然科学基金青年项目,编号81703446,2018/01-2020/01,20万元,在研,主持。
博士后创新人才支持计划,编号BX201600057,2016/8.19-2018/8.19,20万,在研,主持。
博士后面上基金,编号2017M612474,5万元,已结题,主持。
主要学术论文
1.Tan Yang, Yuyuan Chen, Pengxuan Zhao, Huiying Xue, Jia You, Bin Li, Yong Liu, Chuanchuan He, Xiaojuan Zhang, Lingling Fan, Robert J. Lee, Lei Li, Xiang Ma, Chuanrui Xu*, Guangya Xiang*,Enhancing the Therapeutic Effect via Elimination of Hepatocellular Carcinoma Stem Cells using Bmi1 siRNA Delivered by Cationic Cisplatin Nanocapsules,Nanomedicine: Nanotechnology, Biology, and Medicine,2018:14 2009-2021.
2.Yang Tan#,Xu Ling#,Li Bin,Li Weijie,Ma Xiang,Fan Lingling,Robert J Lee,Xu Chuanrui*,Xiang Guangya*,antitumor activity of a folate receptor-targeted immunoglobulin g-doxorubicin conjugate,International Journal of Nanomedicine,2017:12 2505~2515
3.Yang Tan,Zhao Pengxuan,Rong Zhao,Li Bin,Xue Huiying,You Jia,He Chuanchuan,Li Weijie,He Xinxin,Robert J Lee,Ma Xiang*,Xiang Guangya*,Anti-tumor Efficiency of Lipid-coated Cisplatin Nanoparticles Co-loaded with MicroRNA-375,Theranostics,2016, 6(1): 142~154
4.Yang Tan,Li Bin,Qi Shibo,Liu Yong,Gai Yongkang,Ye Peng,Yang Guang,Zhang Wendian,Zhang Peng,He Xingxing,Li Weijie,Zhang Zhiping,Xiang Guangya*,Xu Chuanrui*,Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo,Theranostics,2014,4(11):1096~1111
5.Huang Yifei#,Yang Tan#,Zhang Wendian,Lu Yao,Ye Peng,Yang Guang,Li Bin,Qi Shibo,Liu Yong,He Xingxing,Robert J Lee,Xu Chuanrui*,Xiang Guangya*,a novel hydrolysis-resistant lipophilic folate derivative enables stable delivery of targeted liposomes in vivo,International Journal of Nanomedicine,2014,9:4581~4595
6.Wendian Zhang, Fangqi Peng, Taotao Zhou, Yifei Huang, Li Zhang, Peng Ye, Mao Lu, Yongkang Gai, Tan Yang, Xiang Ma*, Guangya Xiang*, Targeted delivery of chemically modified anti-miR-221 to hepatocellular carcinoma with negatively charged liposomes. International journal of nanomedicine, 2015, 10: 4825.
7. Guang Yang, Tan Yang, Wendian Zhang, Miao Lu, Xiang Ma, aGuangya Xiang, In Vitro and in Vivo Antitumor Effects of Folate-Targeted Ursolic Acid Stealth Liposome, Journal of Agricultural and Food Chemistry, J. Agric. Food Chem. 2014, 62, 2207−2215
8.Peng Ye, Wendian Zhang, Tan Yang, Yao Lu, Miao Lu, Yongkang Gai, Xiang Ma, Guangya Xiang, Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting, International Journal of Nanomedicine, International Journal of Nanomedicine 2014:9 2167–2178
9. Bin Li#, ShiBo Qi#, Tan Yang, Yong Liu, Shanshan Cao, Chuanrui Xu*, Validation of Bmi1 as a Therapeutic Target of Hepatocellular, Int J Mol Sci, 2014:15 20004-21
10.Miao Lu,Wendian Zhang, Yongkang Gai,Tan Yang,Peng Ye, Guang Yang, Xiang Ma* and Guangya Xiang* , Folate–PEG functionalized silica CdTe quantum dots as fluorescent probes for cancer cell imaging. New Journal of Chemistry, 2014, 38(9): 4519-4526.