国家自然科学基金面上项目,81973257,在研,参加
近几年部分研究成果:
(1) Yannan Yang#,Yao Lu #,et al. Stepwise degradable nanocarriers enabled cascade delivery for synergistic cancer therapy.Advanced Functional Materials, (2018),28: 1800706. (共同第一作者)(IF=15.621)
(2)Yao Lu#,Yannan Yang#, et al. Glutathione-Depletion Mesoporous Organosilica Nanoparticles as a Self-Adjuvant and Co-delivery Platform for Enhanced Cancer Immunotherapy.Biomaterials.2018,82-92.(IF= 10.273)
(3) Hao Song, Meihua Yu,Yao Lu, Zhengying Gu, et al. Plasmid DNA Delivery: Nanotopography Matters, Journal of the American Chemical Society, 2017, 139(50): 18247-18254.(IF=14.695)
(4) Yannan Yang#,Yao Lu#, Prasanna Lakshmi Abbaraju, et al. Multi‐shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy, Angewandte Chemie, 2017, 129(29): 8566-8570 (共同第一作者)(IF=12.257)
(5)Yao Lu, Yuhua Wang, Lei Miao, Matthew Haynes, et al. Exploiting in situ antigen generation and immune modulation to enhance chemotherapy response in advanced melanoma: a combination nanomedicine approach,Cancer letters, 2016, 379(1): 32-38.(IF=6.508)
(6)Yao Lu, Lei Miao, Yuhua Wang, Zhenghong Xu, et al. Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model.Molecular Therapy. 2016. 24(2): 364-374 (IF=8.402)
(7)Yao Lu#, Nan Ding#, Chang Yang, Lei Huang L, Jian Liu, Guangya Xiang. Preparation and in vitro Evaluation of a Folate-Linked Liposomal Curcumin Formulation.Journal of Liposome Research.2012, 22, 110-119.
(8) Nan Ding#,Yao Lu#,Robert J Lee#,Chang Yang,Lei Huang,Jian Liu,Guangya Xiang,Folate receptor targeted fluorescent paramagnetic bimodal liposomes for tumor imaging,International Journal of Nanomedicine,2011,6:2513-2520 (共同第一作者)
(9) Peng Ye, Wendian Zhang, Tan Yang,Yao Lu, Mao Lu, Yongkang Gai, Xiang Ma, Guangya Xiang. Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting.International Journal of Nanomedicine. 2014, 9, 2167-2178.