研究方向：
1.急性肾损伤和糖尿病肾病的机制研究
2.多肽药物在肾脏疾病中治疗作用研究
3.糖尿病及代谢综合征的机制研究
联系方式：hongchen2017@hust.edu.cn
工作与教育经历：
2019/11-至今，华中科技大学，药学院，副教授
2017/08-2019/11，华中科技大学，药学院，讲师
2014/07-2017/07，华中科技大学，公共卫生学院，博士后
2009/09-2014/06，华中科技大学，药学院，博士
2004/09-2009/06，沈阳药科大学，药学院，学士
主持科研项目：
1.国家自然科学基金青年项目, 31500941，脂肪因子Apelin对急性肾损伤的保护机制研究
2.华中科技大学自主创新基金面上项目，ELA多肽在急性肾损伤中的作用研究
3.中国博士后科学基金第九批特别资助项目，2016T90692，H3K27甲基化在糖尿病肾病中的作用机制研究
4.中国博士后科学基金面上项目，2015M572149，Apelin对缺血再灌注型急性肾损伤的保护机制研究
代表性研究成果：
(1)Wang Chao#, Xiong Mingrui#, Yang Chen, Yang Dong, Zheng Jiaojiao, Fan Yu, Wang Shun, Gai Yongkang, Lan Xiaoli,Chen Hong*, Zheng Ling*, Huang Kun*, PEGylated and acylated Elabela analogues show enhanced receptor binding, prolonged stability, and remedy of acute kidney injury.J Med Chem, 2020, DOI: 10.1021/acs.jmedchem.0c01913
(2)Chen Hong#,Huang Yixue#, Zhu Xiuqin, Liu Chong, Yuan Yangmian, Su Hua, Zhang Chun, Liu Chengyu, Xiong Mingrui, Qu Yannan, Yun Peng, Zheng Ling*, Huang Kun *, Histone demethylase UTX is a therapeutic target for diabetic kidney disease,The Journal of Physiology,2019, 597(6):1643-1660
(3)Chen Hong, Liu Chengyu, Cheng Cheng, Zheng Ling, Huang Kun*, Effects of apelin peptides on diabetic complications,Curr Protein Pept Sci, 2018, 19(2):179-189
(4)Chen Hong,Wang Lin, Wang Wenjun, Cheng Cheng, Zhang Yu, Zhou Yu, Wang Congyi, Miao Xiaoping, Wang Jiao, Wang Chao, Li Jianshuang, Zheng Ling, Huang Kun*, ELABELA and an ELABELA fragment protect against AKI.J Am Soc Nephrol,2017 Sep; 28(9):2694-2707
(5)Chen Hong, Wan Danyang, Wang Lin, Peng Anlin, Xiao Hongdou, Petersen R.Bobert, Liu Chengyu,Zheng Ling*, Huang Kun*, Apelin protects against acute renal injury by inhibiting TGF-b1,BBA - Molecular Basis of Disease,2015 Jul; 1852(7):1278-87
(6)Chen Hong,Li Jianshuang, Jiao Lihua, Petersen R.Bobert, Li Jiong, Peng Anlin, Zheng Ling*, Huang Kun*, Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse,The Journal of Physiology, 2014, 592, 505-521
(7)Chen Hong#, Zheng Chenghong#, Zhang Xin, Li Jianshuang, Li Jiong, Zheng Ling*, Huang Kun*, Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice,Peptides, 2011, 32, 1634-1639
