张勇慧

二级教授，国务院特殊津贴获得者，药学院院长，教育部特聘教授，国家杰出青年科学基金获得者，科技部“科技创新领军人才”，国家自然科学基金创新群体骨干，湖北省自然科学基金创新群体负责人，教育部“新世纪优秀人才支持计划”、“湖北省杰出青年科学基金”获得者，“湖北省天然药物化学与资源评价重点实验室”主任，“武汉市天然药物工程技术中心”主任。2017年暑期，作为药学代表，参加了北戴河暑期专家休假活动，受到刘云山等中央首长的亲切接见。

中国药学会理事，中国中药和天然药物专业委员会委员，中国医药生物技术协会生物制药技术分会常务委员，湖北省药学会副秘书长、常务理事，湖北省中药和天然药物专业委员会主任委员，武汉市药学会副理事长。国家科技奖励评审专家，教育部科技奖励评审专家，国家CFDA新药审评专家，国家CFDA化妆品审评专家，国家重大新药创制专项“十二五”《糖尿病新药临床前研究》课题组长。湖北省药学一级重点学科负责人，中药学湖北省品牌专业负责人，人民卫生出版社2016版《天然药物化学》副主编。华中科技大学学报医学版（SCI收录）副主编，药学学报B(影响因子6.0)编委，Sci. Rep. (影响因子4.1)编委，药学进展编委。

主持国家“重大新药创制”专项课题3项，国家高技术研究发展计划（863计划）1项，国家自然科学基金项目7项，多项省市级科研项目及企业合作项目。申请专利16项，发表论文220余篇，其中SCI收录论文150余篇，副主编或参加编写国家级教材或配套教材9部。2018年获华中科技大学三育人奖，2011年获湖北省科技进步二等奖。

主要从事天然药物生物活性成分及创新药物研究，分离和鉴定了天然产物2000余个，其中新化合物800个，包括具有全新碳架的PPAPs、细胞松弛素、萜类、聚酮等130个，隶属于67个不同的新骨架类型。其中14个化合物被Nat. Prod. Rep.评为热点化合物（Hot off the press），有药用开发前景的天然产物或衍生物8个，在复杂天然产物的结构鉴定及活性研究、微量天然产物活性筛选及作用靶点确证、活性化合物深入药理及作用机制研究等方面取得了较好的成绩。共发表通讯作者SCI论文150余篇，包括Hepatology 1篇(14.0)、Angew. Chem. 4篇(12.1)、Nucleic Acids Res.1篇(11.5)、Chem. Sci. 1篇(9.0)、Org. Lett. 13篇(6.4)、Org. Chem. Front.2篇(5.4)、J. Org. Chem. 3篇(4.8)、Brit. J. Pharmacol. 1篇(6.8)、Carcinogenesis 1篇(5.0)、J. Nat. Prod. 14篇(3.8)、Phytochemistry4篇(3.1)、RSC Adv.4篇(2.9)等。

诚挚欢迎国内外具有天然药物化学、药理、药物化学、有机合成或生物合成等研究背景的科研工作者加入本课题组从事博士后研究，待遇从优！

E-mail：zhangyh@mails.tjmu.edu.cn

地址：武汉市航空路13号(邮编430030)

(一)近年主持的主要科研项目

国家杰出青年基金《天然药物化学》400万

国家重大新药创制科技重大专项《化药1.1类抗肝纤维化新药金线莲苷临床前研究》290万

湖北省技术创新专项重大项目《化药1.1类抗肝纤维化新药金线莲苷临床前研究》200万

湖北省自然科学基金创新群体《重大疾病的创新药物和转化医学研究》20万

国家自然科学基金《黄柄曲霉新颖次生代谢产物化学成分及生物活性研究》78万

国家高技术研究发展计划（863计划）《促肝细胞再生金线莲胶囊保健品》625万

国家重大新药创制专项课题《糖尿病新药临床前研究》2291万元

国家自然科学基金《肉桂和川桂中抗肿瘤二萜化学成分及作用机制研究》80万

科技部中韩国际合作项目《化药一类降血糖新药KD10临床前研究》90万

国家重大新药创制专项《中药6.1类治疗类风湿关节炎新药复方鹿角霜片临床前研究》150万

教育部新世纪优秀人才支持计划《楮头红保护肝损伤的活性成分及作用机制研究》50万

（二）近年发表的主要论文

[1]张勇慧，微生物来源的活性天然产物的研究，药学进展，2018,42 (1):1-3.

[2]Changxing Qi^(#), Mengting Liu^(#), Qun Zhou^(#), Weixi Gao, Chunmei Chen, Yongji Lai, Zhengxi Hu, Yongbo Xue, Jinwen Zhang, Dongyan Li, Xiao-Nian Li, Qing Zhang, Jianping Wang^(*), Hucheng Zhu^(*), andYonghui Zhang^(*).BACE1 Inhibitory Meroterpenoids fromAspergillus terreus.Journal of Natural Products,accepted, DOI: 10.1021/acs.jnatprod.7b01050.

[3]Changxing Qi, Weixi Gao, Jianping Wang, Mengting Liu, Jinwen Zhang, Chunmei Chen, Zhengxi Hu, Yongbo Xue, Dongyan Li, Qing Zhang, Yongji Lai, Qun Zhou^(*), Hucheng Zhu^(*), andYonghui Zhang^(*).Terrusnolides A-D, new butenolides with anti-inflammatory activities from an endophyticAspergillusfromTripterygium wilfordii.Fitoterapia, 2018, 130, 134–139.

[4]Changxing Qi^(#), Qun Zhou^(#),Yuan Zhou, Zengwei Luo, Chong Dai, Hucheng Zhu, Chunmei Chen, Yongbo Xue, Jianping Wang, Yafen Wang, Yaping Liu, Ming Xiang, Weiguang Sun, Jinwen Zhang^(*), andYonghui Zhang^(*). Kinsenoside: A Promising Bioactive Compound fromAnoectochilusSpecies.Current Medical science, 2018, 1, 11–18.

[5]Mengting Liu^(#), Weiguang Sun^(#), Jianping Wang^(#), Yan He, Jinwen Zhang, Fengli Li, Changxing Qi, Hucheng Zhu, Yongbo Xue, Zhengxi Hu^(*)，andYonghui Zhang^(*), Bioactive secondary metabolites from the marine-associated fungusAspergillus terreus, Bioorganic Chemistry, 2018, 80, 525-530.

[6]Mengting Liu^(#), Changxing Qi^(#), Weiguang Sun^(#), Ling Shen, Jianping Wang, Junjun Liu, Yongji Lai, Yongbo Xue, Zhengxi Hu^(*)andYonghui Zhang^(*),α-Glucosidase Inhibitors from the Coral-Associated FungusAspergillus terreus, Frontiers in chemistry, doi: 10.3389/fchem.2018.00422

[7]Qing Zhang, Beiye Yang, Fengli Li, Mengting Liu, Shuang Lin, Jianping Wang, Yongbo Xue, Hucheng Zhu, Weiguang Sun^(*), Zhengxi Hu^(*),Yonghui Zhang^(*), Mycophenolic Acid Derivatives with Immunosuppressive Activity from the Coral-Derived Fungus Penicillium bialowiezense, 2018, Marine Drugs, 16, 230.

[8]Zheng-Xi Hu, Hou-Chao Xu, Kun Hu, Miao Liu, Xiao-Nian Li, Xing-Ren Li, Xue Du,Yong-Hui Zhang^(*), Pema-Tenzin Puno^(*), Han-Dong Sun, Structurally diverse diterpenoids from Isodon pharicus, 2018, Organic Chemistry Frontiers, 5, 2379–2389.

[9]Zhengxi Hu^(#), Weiguang Sun^(#), Fengli Li^(#), Jiankun Guan^(#), Yuanyuan Lu, Junjun Liu, Ying Tang, Guang Du, Yongbo Xue, Zengwei Luo, Jianping Wang^(*), Hucheng Zhu^(*), andYonghui Zhang^(*), Fusicoccane-Derived Diterpenoids fromAlternaria brassicicola: Investigation of the Structure-Stability Relationship and Discovery of a IKKβ Inhibitor,Organic Letters, 2018, 20, 5198–5202.

[10]Huaqiang Li^(#), Weiguang Sun^(#), Mengyi Deng^(#), Qun Zhou, Jianping Wang, Junjun Liu, Chunmei Chen, Changxing Qi, Zengwei Luo, Yongbo Xue^(*), Hucheng Zhu^(*), andYonghui Zhang^(*), Asperversiamides, Linearly Fused Prenylated Indole Alkaloids from the Marine-Derived Fungus Aspergillus versicolor, Journal of Organic Chemistry, 2018, 83, 8483−8492.

[11]Linzhen Hu^(#), Yanfei Liu^(#), Yanxing Wang, Zhenzhen Wang, Jinfeng Huang, Yongbo Xue, Junjun Liu, Zhenming Liu^(*), Yong Chen^(*),Yonghui Zhang^(*), Discovery of acylphloroglucinol-based meroterpenoid enantiomers as KSHV inhibitors from Hypericum japonicum, RSC Advances, 2018, 8, 24101.

[12]Wenjing Wang, Jiaojiao Gong, Xiaorui Liu, Chong Dai, Yanyan Wang, Xiaonian Li, Jianping Wang, Zengwei Luo, Yuan Zhou, Yongbo Xue, Hucheng Zhu, Chunmei Chen^(*),Yonghui Zhang^(*), Cytochalasans produced by the co-culture of Aspergillus flavipes and Chaetomium globosum, Journal of Natural Products, 2018, 81, 1578–1587.

[13]Huaqiang Li, Weiguang Sun, Mengyi Deng, Changxing Qi, Chunmei Chen, Hucheng Zhu, Zengwei Luo, Jianping Wang^(*), Yongbo Xue^(*), andYonghui Zhang^(*), Asperversins A and B, two novel meroterpenoids with an unusual 5/6/6/6 ring from the marine-derived fungus Aspergillus versicolor, Marine Drugs, 2018, 16, 177.

[14]Yuben Qiao^(#), Yanfei Liu^(#), Xueyan Duan, Chunmei Chen, Junjun Liu, Hucheng Zhu, Yongbo Xue^(*),Yonghui Zhang^(*), A pair of epimeric cassane-type diterpenoids and a new labdane-type derivative fromCaesalpinia decapetala, Tetrahedron, 2018, 74, 3852-3857.

[15]Zhaodi Wu, Yongji Lai, Qing Zhang, Shuangshuang Xie, Mi Zhang, Zhengxi Hu, Xiao-Nian Li, Jianping Wang, Zengwei Luo, Yongbo Xue, Qun Zhou, Hucheng Zhu,Yonghui Zhang^(*), Phenylacetylene-bearing3,4-seco-cleistanthane diterpenoids from the roots ofPhyllanthus glaucus, Fitoterapia, 2018, 128, 79–85.

[16]Keliang Chen^(#), Weiguang Sun^(#), Qiong Bie, Xiulan Liu, Chunmei Chen, Junjun Liu, Yongbo Xue, Jianping Wang, Zengwei Luo, Hucheng Zhu^(*),Yonghui Zhang^(*), Fusopoltide A and fusosterede A, A polyketide with a pentaleno[1,2-c]pyran ring system and A degraded steride, from the fungusFusarium solani, Tetrahedron Letters, 2018, 59, 2679-2682.

[17]Zheng-Xi Hu, Miao Liu, Wei-Guang Wang, Xiao-Nian Li, Kun Hu, Xing-Ren Li, Xue Du,Yong-Hui Zhang^(*), Pema-Tenzin Puno^(*), and Han-Dong Sun. 7α,20-Epoxy-ent-kaurane Diterpenoids from the Aerial Parts of Isodon pharicus. Journal of Natural Products 2018, 81, 106-116.

[18]Qingyi Tong^(#), Huijuan You^(#), Xintao Chen, Kongchao Wang, Weiguang Sun, Yufeng Pei, Xiaodan Zhao, Ming Yuan, Hucheng Zhu, Zengwei Luo^(*),Yonghui Zhang^(*), ZYH005, a novel DNA intercalator, overcomes all-transretinoic acid resistance in acute promyelocytic leukemia, Nucleic Acids Research, 2018, 7, 3284-3297.

[19]Shuangshuang Xie^(#), Ye Wu^(#), Yuben Qiao, Yi Guo, Jianping Wang, Zhengxi Hu, Qing Zhang, Xiaonian Li, Jinfeng Huang, Qun Zhou, Zengwei Luo, Junjun Liu, Hucheng Zhu, Yongbo Xue^(*),Yonghui Zhang^(*), Protoilludane, Illudalane, and Botryane Sesquiterpenoids from the Endophytic FungusPhomopsissp. TJ507A,J. Nat. Prod.,2018, 81, 1311−1320.

[20]Wenjing Wang, Xiao Wan, Junjun Liu, Jianping Wang, Hucheng Zhu, Chunmei Chen^(*),Yonghui Zhang^(*), Two New Terpenoids from Talaromyces purpurogenus, Marine Drugs, 2018,16, 150.

[21]Xuwen Zhang, Zhaodi Wu, Yongji Lai, Dongyan Li, Jianping Wang, Zengwei Luo, Yongbo Xue, Hucheng Zhu, Chunmei Chen^(*), andYonghui Zhang^(*), (±)-Terreinlactone A, A Pair of 3-Substituted δ-Lactone Enantiomers Derived from Terrein from the Fungus Aspergillus terreus, Chemical and Pharmaceutical Bulletin, 2018,66(7): 764-767.

[22]Beiye Yang^(#), Weiguang Sun^(#), Jianping Wang^(#), Shuang Lin, Xiao-Nian Li, Hucheng Zhu, Zengwei Luo, Yongbo Xue, Zhengxi Hu^(*),Yonghui Zhang^(*), A New Breviane Spiroditerpenoid from the Marine- Derived Fungus Penicillium sp. TJ403-1, Marine Drugs, 2018,16, 110.

[23]Yi Zang, Gregory Genta-Jouve, Yingyu Zheng, Qing Zhang, Chunmei Chen, Qun Zhou, Jianping Wang^(*), Hucheng Zhu^(*),Yonghui Zhang^(*). Griseofamines A and B: Two indole-tetramic acid alkaloids with 6/5/6/5 and 6/5/7/5 ring systems from Penicillium griseofulvum. Organic Letters, 2018, 20, 2046-2050.

[24]Mengting Liu^(#), Qun Zhou^(#), Jianping Wang^(#), Junjun Liu, Changxing Qi, Yongji Lai, Hucheng Zhu, Yongbo Xue, Zhengxi Hu^(*)andYonghui Zhang^(*), Anti-inflammatory butenolide derivatives from the coral-derived fungus Aspergillus terreus and structure revisions of aspernolides D and G, butyrolactone VI and 4',8''-diacetoxy butyrolactone VI, RSC Advances, 2018, 8, 13040–13047.

[25]Yuben Qiao^(#), Xiaotian Zhang^(#), Yan He^(#), Weiguang Sun^(#), Wenya Feng, Junjun Liu, Zhengxi Hu, Qianqian Xu, Hucheng Zhu, Jinwen Zhang, Zengwei Luo, Jianping Wang^(*), Yongbo Xue^(*), andYonghui Zhang^(*), Aspermerodione, a novel fungal metabolite with an unusual 2,6-dioxabicyclo[2.2.1]heptane skeleton, as an inhibitor of penicillin-binding protein 2a, Scientific Reports, 2018, 8, 5454.

[26]Huiling Wen, Xiaorui Liu, Qing Zhang, Yanfang Deng, Yi Zang, Jianping Wang, Junjun Liu, Qun Zhou, Linzhen Hu, Hucheng Zhu, Chunmei Chen^(*), andYonghui Zhang^(*),Three New Indole Diketopiperazine Alkaloids fromAspergillus ochraceus, Chemistry & Biodiversity, 2018, 15,, e1700550.

[27]Kongchao Wang^(#), Xia Chen^(#), Ming Yuan, Meng Yao, Hucheng Zhu, Yongbo Xue, Zengwei Luo^(*), andYonghui Zhang^(*), Silver-mediated Cyanomethylation of Cinnamamides by Direct C(sp3)–H Functionalization of Acetonitrile, The Journal of Organic Chemistry, 2018, 83, 1525–1531.

[28]Dongyan Li,Guang Du, Xuepeng Gong, Jieru Guo, Jinwen Zhang, Chunmei Chen, Yongbo Xue, Hucheng Zhu^(*), andYonghui Zhang^(*), Hyperattenins L and M, two new polyprenylated acylphloroglucinols with adamantyl and homoadamantyl core structures fromHypericum attenuatum, Fitoterapia, 2018,125, 130–134.

[29]Shupeng Zou^(#), Zhongbo Wang^(#), Jing Wang^(#), Guangzheng Wei, Wenjing Wang, Yi Zang, Fanrong Zeng, Keliang Chen, Junjun Liu, Jianping Wang, Zengwei Luo, Yongbo Xue, Hucheng Zhu, Chunping Yin^(*), Chunmei Chen^(*), andYonghui Zhang^(*), Azacoccones A−E, Five Unexpected Aza-epicoccone Derivatives fromAspergillus flavipes, 2018, Fitoterapia, 124, 127–131.

[30]Keliang Chen^(#), Xuwen Zhang^(#), Weiguang Sun^(#), Junjun Liu, Jing Yang, Chunmei Chen, Xiulan Liu, Limin Gao, Jianping Wang, Hua Li, Zengwei Luo, Yongbo Xue, Hucheng Zhu^(*), andYonghui Zhang^(*), Manginoids A–G: Seven Monoterpene-Shikimate-Conjugated Meroterpenoids with a Spiro Ring System fromGuignardia mangiferae, Organic Letters, 2017, 19 (21), 5956–5959.

[31]Peng Zhou^(#), Zhaodi Wu^(#), Dongdong Tan, Jing Yang, Qun Zhou, Fanrong Zeng, Mi Zhang, Qiong Bie, Chunmei Chen, Yongbo Xue, Zengwei Luo, Jianping Wang^(*), Hucheng Zhu^(*),Yonghui Zhang^(*), Atrichodermones A–C, three new secondary metabolites from the solid culture of an endophytic fungal strain,Trichoderma atroviride, Fitoterapia, 2017, 123, 18–22.

[32]Yan He^(#), Zhengxi Hu^(#), Qin Li^(#), Jinfeng Huang, Xiao-Nian Li, Hucheng Zhu, Junjun Liu, Jianping Wang^(*), Yongbo Xue^(*), andYonghui Zhang^(*), Bioassay-Guided Isolation of Antibacterial Metabolites from Emericella sp. TJ29, Journal Natural Products, 2017, 80, 2399−2405.

[33]Guangzheng Wei^(#), Chunmei Chen^(#), Qingyi Tong^(#), Jinfeng Huang, Wenjing Wang, Zhaodi Wu, Jing Yang, Junjun Liu, Yongbo Xue, Zengwei Luo, Jianping Wang, Hucheng Zhu^(*), andYonghui Zhang^(*), Aspergilasines A–D: four merocytochalasans with new carbon skeletons fromAspergillus flavipesQCS12, Organic Letters, 2017, 19, 4399−4402.

[34]Jie Cao^(#), Limin Gao^(#), Yizhan Chen^(#), Weiguang Sun, Fuqian Wang, Hua Li^(*),Yonghui Zhang^(*), Citrinal B, natural 11 beta-hydroxysteroid dehydrogennase type 1 inhibitor identified from structure-based virtual screening, Fitoterapia, 2017, 123, 29–34.

[35]Zheng-Xi Hu, Xiao-Nian Li, Yi-Ming Shi, Wei-Guang Wang, Xue Du, Yan Li,Yong-Hui Zhang^(*), Jian-Xin Pu^(*), Han-Dong Sun, Lanostane-type triterpenoids from Kadsura coccinea, Tetrahedron, 2017, 73, 2931–2937.

[36]Lei Zhou, Yali Tuo, Xiaoman Guo, Wei Tang, Yongbo Xue, Junfen Zeng, Yu Zhou, Ming Xiang, Jianping Zuo, Guangmin Yao^(*),Yonghui Zhang^(*), Cinnamomols A and B, Immunostimulative Diterpenoids with a New Carbon Skeleton from the Leaves ofCinnamomum cassia, Organic Letters, 2017, 19, 3029−3032.

[37]Hucheng Zhu^(#), Chunmei Chen^(#), Qingyi Tong^(#), Jing Yang, Guangzheng Wei, Yongbo Xue, Jianping Wang, Zengwei Luo, andYonghui Zhang^(*), Asperflavipine A: A Cytochalasan Heterotetramer Uniquely Defined by a Highly Complex Tetradecacyclic Ring System from Aspergillus flavipes QCS12, Angewandte Chemie-International Edition, 2017, 56, 5242 –5246.

[38]Yuan-Yuan Lu^(#), Xue-Peng Gong^(#), Yong-Bo Xue, Hu-Cheng Zhu, Xiao-Nian Li, Lin-Zhen Hu, Jian-Kun Guan, Jin-Wen Zhang^(*), Guang Du^(*),Yong-Hui Zhang^(*), Two pairs of chlorine-containing phenylpropanoid enantiomers fromAcorus tatarinowii, Chinese Chemical Letters, 2017, 28, 1460-1464.

[39]Yi Guo, Na Zhang, Chunmei Chen, Jinfeng Huang, Xiao-Nian Li, Junjun Liu, Hucheng Zhu, Qingyi Tong, Jinwen Zhang, Zengwei Luo, Yongbo Xue^(*), andYonghui Zhang^(*), Tricyclic Polyprenylated Acylphloroglucinols from St John’s Wort,Hypericum perforatum, Journal of Natural Products, 2017, 80, 1493−1504.

[40]Yan He^(#), Mengzhu Zheng^(#), Qin Li^(#), Zhengxi Hu, Hucheng Zhu, Junjun Liu, Jianping Wang, Yongbo Xue^(*), Hua Li^(*), andYonghui Zhang^(*), Asperspiropene A, a novel fungal metabolite as an inhibitor of cancer-associated mutant isocitrate dehydrogenase 1, Organic Chemistry Frontiers, 2017, 2017, 4, 1137–1144.

[41]Yan He^(#), Zhengxi Hu^(#), Weiguang Sun, Qin Li, Xiao-Nian Li, Hucheng Zhu, Jinfeng Huang, Junjun Liu, Jianping Wang, Yongbo Xue^(*), andYonghui Zhang^(*), Spiroaspertrione A, a Bridged Spirocyclic Meroterpenoid as a Potent Potentiator of Oxacillin against Methicillin-Resistant Staphylococcus aureus from Aspergillus sp. TJ23, The Journal of Organic Chemistry,2017, 82, 3125–3131.

[42]Jun-Fen Zeng, Hu-Cheng Zhu, Jian-Wu Lu, Lin-Zhen Hu, Jin-Chun Song^(*), andYong-Hui Zhang^(*), Two new geranylphenylacetate glycosides from the barks ofCinnamomum cassia,Natural Product Research, 2017, 31, 1812–1818.

[43]Fuqian Wang^(#), Haoran Ma^(#), Zhengxi Hu, Jie Jiang, Hucheng Zhu, Lu Cheng, Quanwei Yang, Hong Zhang^(*), Geng Zhang^(*), andYonghui Zhang^(*), Secondary metabolites from Colletotrichum capsici, an endophytic fungus derived fromSiegesbeckia pubescensMakino,Natural Product Research, 2017,31, 1849-1854.

[44]Guangzheng Wei^(#), Dongdong Tan^(#), Chunmei Chen^(#), Qingyi Tong, Xiao-Nian Li, Jinfeng Huang, Junjun Liu, Yongbo Xue, Jianping Wang, Zengwei Luo, Hucheng Zhu^(*), andYonghui Zhang^(*), Flavichalasines A–M, cytochalasan alkaloids fromAspergillus flavipes,Scientific Reports, 2017, 7: 42434.

[45]Hucheng Zhu^(#), Chunmei Chen^(#), Jinwen Zhang, Yi Guo, Dongdong Tan, Guangzheng Wei, Jing Yang, Jianping Wang, Zengwei Luo, Yongbo Xue^(*), andYonghui Zhang^(*), Hyperisampsins N and O, Two New Benzoylated Phloroglucinol Derivatives fromHypericum sampsonii, Chinese Chemical Letters, 2017, 28, 986-990.

[46]Zhengxi Hu^(#), Ye Wu^(#), Shuangshuang Xie, Weiguang Sun, Yi Guo, Xiao-Nian Li, Junjun Liu, Hua Li, Jianping Wang, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic FungusPhomopsissp. TJ507A,Organic Letters, 2017, 19(1): 258–261.

[47]Yuben Qiao^(#), Qianqian Xu^(#), Zhengxi Hu, Xiao-Nian Li, Ming Xiang, Junjun Liu, Jinfeng Huang, Hucheng Zhu, Jianping Wang, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), Diterpenoids of the Cassane Type fromCaesalpinia decapetala,Journal of Natural Products, 2016, 79, 3134–3142.

[48]Zheng-Xi Hu, Kun Hu, Yi-Ming Shi, Wei-Guang Wang, Xue Du, Yan Li,Yong-Hui Zhang^(*), Jian-Xin Pu^(*),and Han-Dong Sun, Rearranged 6/6/5/6-Fused Triterpenoid Acids from the Stems ofKadsura coccinea,Journal of Natural Products, 2016, 79, 2590–2598.

[49]Ming Xiang^(#), Tingting Liu^(#), Wanyue Tan, Hongyu Ren, Hua Li, Junjun Liu, Hui Cao, Qi Cheng, Xiulan Liu, Hucheng Zhu, Yali Tuo, Jianping Wang, andYonghui Zhang^(*),Effects of kinsenoside, a potential immunosuppressive drug for autoimmune hepatitis, on DCs-CD8⁺T cells communication, Hepatology, 2016, 64, 2135-2150.

[50]Hucheng Zhu^(#), Chunmei Chen^(#), Dongdong Tan, Dongyan Li, Yi Guo, Guangzheng Wei, Jinwen Zhang, Jianping Wang, Zengwei Luo, Yongbo Xue^(*), andYonghui Zhang^(*), Sampbenzophenones A–G, prenylated benzoylphloroglucinol derivatives fromHypericum sampsonii,RSC Adv., 2016, 6, 86710-86716.

[51]Fuqian Wang, Hucheng Zhu, Haoran Ma, Jie Jiang, Weiguang Sun, Lu Cheng, Geng Zhang^(*),Yonghui Zhang⁽*⁾, Citrinal B, a new secondary metabolite from endophytic fungusColletotrichum capsiciand structure revision of citrinal A,Tetrahedron Letters, 2016, 57, 4250–4253. (Front cover)

[52]Jing Wang, Dongdong Tan, Guangzheng Wei, Yi Guo, Chunmei Chen, Hucheng Zhu, Yongbo Xue, Chunping Yin⁽*⁾, andYonghui Zhang⁽*⁾. Studies on the Chemical Constituents ofCuscuta chinensis. Chemistry of Natural Compounds, 2016, 52(6): 1133–1136.

[53]Changxing Qi^(#), Jian Bao^(#), Jianping Wang^(#), Hucheng Zhu, Yongbo Xue, Xiaochuan Wang, Hua Li, Weiguang Sun, Weixi Gao, Yongji Lai, Jian-Guo Chen, andYonghui Zhang⁽*⁾, Asperterpenes A and B, Two Unprecedented Meroterpenoids fromAspergillus terreuswith BACE1 Inhibitory Activities,Chemical Science, 2016, 7, 6563-6572.

[54]Hucheng Zhu^(#), Chunmei Chen^(#), Jing Yang^(#), Dongyan Li, Jinwen Zhang, Yi Guo, Jianping Wang, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), Hyperhexanone A, a crucial intermediate from bicyclo[3.3.1]- to cyclohexanone monocyclic-polycyclic polyprenylated acylphloroglucinols,Tetrahedron, 2016, 72, 4655–4659.

[55]Yongji Lai, Hong Zeng, Meijun He, Huiqin Qian, Zhaodi Wu, Zengwei Luo, Yongbo Xue, Guangmin Yao^(*),Yonghui Zhang^(*), 6,8-Di-C-methyl-flavonoids with neuroprotective activities fromRhododendron fortune, Fitoterapia, 2016, 112, 237–243.

[56]Linzhen Hu^(#), Hucheng Zhu^(#), Lei Li^(#), Jinfeng Huang, Weiguang Sun, Junjun Liu, Hua Li, Zengwei Luo, Jianping Wang, Yongbo Xue^(*), Yu Zhang^(*), andYonghui Zhang^(*), (±)-Japonones A and B, two pairs of new enantiomers with anti-KSHV activities fromHypericum japonicum,Scientific Reports, 2016, 6: 27588.

[57]Qi Ye^(#), Jue jiang^(#), Guanqun Zhan^(#), Wanyao Yan, Liang Huang, Yufeng Hu, Hexiu Su, Qingyi Tong, Ming Yue, Hua Li, Guangmin Yao,Yonghui Zhang^(*), and Hudan Liu^(*), Small molecule activation of NOTCH signaling inhibits acute myeloid leukemia,Scientific Reports, 2016, 6, 26510.

[58]Weiguang Sun^(#), Xintao Chen^(#), Qingyi Tong^(#), Hucheng Zhu^(#), Yan He, Liang Lei, Yongbo Xue, Guangmin Yao, Zengwei Luo, Jianping Wang^(*), Hua Li^(*),Yonghui Zhang^(*), Novel small molecule 11β-HSD1 inhibitor from the endophytic fungusPenicillium commune,Scientific Reports, 2016, 6, 26418.

[59]Linzhen Hu^(#), Yu Zhang^(#), Hucheng Zhu, Junjun Liu, Hua Li, Xiao-Nian Li, Weiguang Sun, Junfen Zeng, Yongbo Xue,Yonghui Zhang^(*), Filicinic Acid-based Meroterpenoids with Anti-Epstein-Barr virus Activities fromHypericum japonicum,Organic Letters, 2016, 18, 2272-2275.

[60]Linzhen Hu, Yongbo Xue, Jinwen Zhang, Hucheng Zhu, Chunmei Chen, Xiao−Nian Li, Junjun Liu, Zhenzhen Wang, Yu Zhang^(*),Yonghui Zhang^(*), (±)-Japonicols A–D, Acylphloroglucinol-based Meroterpenoid Enantiomers with Anti-KSHV Activities fromHypericum japonicum,Journal of Natural Products, 2016, 79, 1322-1328.

[61]Linzhen Hu, Kongchao Wang, Zhenzhen Wang, Junjun Liu, Kaiping Wang, Jinwen Zhang, Zengwei Luo, Yongbo Xue, Yu Zhang^(*),Yonghui Zhang^(*), A New Megastigmane Sesquiterpenoid fromZanthoxylum schinifoliumSieb. et Zucc.,Molecules2016,21, 383.

[62]Linzhen Hu, Zhenzhen Wang, Jinwen Zhang, Yuanyuan Lu, Kaiping Wang, Yongbo Xue, Yu Zhang^(*), andYonghui Zhang^(*), Two New Bioactiveα-Pyrones fromHypericum japonicum,Molecules2016,21, 515.

[63]Zheng-Xi Hu^(#), Yi-Ming Shi^(#), Wei-Guang Wang, Jian-Wei Tang, Min Zhou, Xue Du,Yong-Hui Zhang^(*), Jian-Xin Pu^(*), and Han-Dong Sun, Structural Characterization of Kadcoccinin A: A Sesquiterpenoid with a Tricyclo[4.4.0.0^3,10]decane Scaffold fromKadsura coccinea, Organic Letters, 2016, 18, 2284-2287.

[64]Zhaodi Wu^(#), Yongji Lai^(#), Lei Zhou, Ye Wu, Hucheng Zhu, Zhengxi Hu, Jing Yang, Jinwen Zhang, Jianping Wang, Zengwei Luo, Yongbo Xue^(*), andYonghui Zhang^(*), Enantiomeric Lignans and Neolignans from Phyllanthus glaucus: Enantioseparation and Their Absolute Configurations, Scientific Reports, 2016, 6: 24809.

[65]Yan He^(#), Jun Tian^(#), Xintao Chen, Weiguang Sun, Hucheng Zhu, Qin Li, Liang Lei, Guangmin Yao, Yongbo Xue, Jianping Wang^(*), Hua Li^(*), andYonghui Zhang^(*), Fungal naphtho-γ-pyrones: Potent antibiotics for drug-resistant microbial pathogens, Scientific Reports, 2016, 6: 24291.

[66]Ying Tang^(#), Yongbo Xue^(#), Guang Du^(#), Jianping Wang, Junjun Liu, Bin Sun, Xiao-Nian Li, Guangmin Yao, Zengwei Luo,Yonghui Zhang^(*), Structural Revisions of a Class of Natural Products: Scaffolds of Aglycon Analogues of Fusicoccins and Cotylenins Isolated from Fungi, Angewandte Chemie International Edition, 2016, 55: 4069-4073.

[67]Hucheng Zhu^(#), Chunmei Chen^(#), Qingyi Tong, Xiao-Nian Li, Jing Yang, Yongbo Xue, Zengwei Luo, Jianping Wang, Guangmin Yao,Yonghui Zhang^(*), Epicochalasines A and B: Two Bioactive Merocytochalasans Bearing Caged Epicoccine Dimer Units from Aspergillus flavipes, Angewandte Chemie-International Edition, 2016, 55: 3486–3490

[68]Yuanyuan Lu, Yongbo Xue, Shenjie Chen, Hucheng Zhu, Jinwen Zhang, Xiao-Nian Li, Jianping Wang, JunJun Liu, Changxing Qi, Guang Du^(*),Yonghui Zhang^(*), Antioxidant Lignans and Neolignans from Acorus tatarinowii, Scientific Reports, 2016; 6: 22909.

[69]Geng Zhang, Haoran Ma, Song Hu, Hongfeng Xu, Bo Yang, Quanwei Yang, Yongbo Xue, Lu Cheng, Jie Jiang, Jinwen Zhang, Fuqian Wang^(*),Yonghui Zhang^(*), Clerodane-type diterpenoids from tuberous roots of Tinospora sagittata (Oliv.) Gagnep, Fitoterapia, 2016, 110: 59-65.

[70]Chunmei Chen^(#), Jing Wang^(#), Hucheng Zhu, Jianping Wang, Yongbo Xue, Guangzheng Wei, Yi Guo, Dongdong Tan, Jinwen Zhang, Chunping Yin^(*),Yonghui Zhang^(*), Chaephilones A and B, two new azaphilonederivatives isolated from Chaetomium globosum, Chemistry & Biodiversity, 2016, 13, 422-426.

[71]Chunmei Chen^(#), Qingyi Tong^(#), Hucheng Zhu, Dongdong Tan, Jinwen Zhang, Yongbo Xue, Guangmin Yao, Zengwei Luo, Jianping Wang^(*), Yanyan Wang^(*),Yonghui Zhang^(*), Nine newcytochalasan alkaloids from Chaetomium globosum TW1-1 (Ascomycota, Sordariales), Scientific Reports, 2016, 6: 18711.

[72]Shaheed Ur Rehman, In Sook Kim, Min Sun Choi, Zengwei Luo, Guangming Yao, Yongbo Xue,Yonghui Zhang, Hye Hyun Yoo^(*), Development of a hydrophilic interaction liquid chromatography–tandem mass spectrometric method for the determination of kinsenoside, an antihyperlipidemic candidate, in rat plasma and its application to pharmacokinetic studies, Journal of Pharmaceutical and Biomedical Analysis, 2016, 120: 19-24.

[73]Shaheed Ur Rehman, In Sook Kim, Min Sun Choi, Zengwei Luo, Guangming Yao, Yongbo Xue,Yonghui Zhang^(*), Hye Hyun Yoo^(*), Evaluation of metabolic stability of kinsenoside, an antidiabetic candidate, in rat and human liver microsomes. Mass Spectrometry Letters, 2015, 6(2): 48–51.

[74]Jieru Guo^(#), Jun Tian^(#), Guangmin Yao, Hucheng Zhu, Yongbo Xue, Zengwei Luo, Jinwen Zhang, Yuan Zhang^(*),Yonghui Zhang^(*), Three New 1α–alkyldaphnane-type Diterpenoids fromthe Flower Buds of Wikstroemia chamaedaphne, Fitoterapia, 2015, 106: 242-246.

[75]Hucheng Zhu^(#), Chunmei Chen^(#), Yongbo Xue^(#), Qingyi Tong, Xiao-Nian Li, Xintao Chen, Jianping Wang, Guangmin Yao, Zengwei Luo,Yonghui Zhang^(*), Asperchalasine A, a Cytochalasan Dimer with an Unprecedented Decacyclic Ring System, from Aspergillus flavipes, Angewandte Chemie International Edition, 2015, 54: 13374-13378.

[76]Zheng-Xi Hu^(#), Yi-Ming Shi^(#), Wei-Guang Wang, Xiao-Nian Li, Xue Du, Miao Liu, Yan Li, Yong-Bo Xue,Yong-Hui Zhang^(*), Jian-Xin Pu^(*), Han-Dong Sun, Kadcoccinones A-F, New Biogenetically Related Lanostane-Type Triterpenoids with Diverse Skeletons from Kadsura coccinea, Organic Letters, 2015, 17(18): 4616-4619.

[77]Yuanyuan Lu^(#), Yongbo Xue^(#)(*), Junjun Liu, Guangmin Yao, Dongyan Li, Bin Sun, Jinwen Zhang, Yanfei Liu, Changxing Qi, Ming Xiang, Zengwei Luo, Guang Du^(*),Yonghui Zhang^(*), (+/-)-Acortatarinowins A-F, Norlignan, Neolignan, and Lignan Enantiomers from Acorus tatarinowii, Journal of Natural Products, 2015, 78(9): 2205-2214.

[78]Hucheng Zhu^(#), Chunmei Chen^(#), Qingyi Tong, Xintao Chen, Jing Yang, Junjun Liu, Bin Sun, Jianping Wang, Guangmin Yao, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), Hyperisampsins H-M, Cytotoxic Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii, Scientific Reports, 2015, 5: 14772.

[79]Xincai Hao, Jing Chen, Yongji Lai, Ming Sang, Guangmin Yao, Yongbo Xue, Zengwei Luo, Geng Zhang^(*),Yonghui Zhang^(*), Chemical constituents from leaves of Cinnamomum subavenium, Biochemical Systematics and Ecology, 2015, 61: 156-160.

[80]Liang Lei^(#), Yong-bo Xue^(#), Zhong Liu, Si-si Peng, Yan He, Yang Zhang, Rong Fang, Jian-ping Wang, Zeng-wei Luo, Guang-min Yao, Jin-wen Zhang, Geng Zhang, Hong-ping Song^(*),Yong-hui Zhang^(*), Coumarin derivatives from Ainsliaea fragrans and their anticoagulant activity., Scientific Reports, 2015, 5: 13544.

[81]Yongji Lai, Tingting Liu, Rongjian Sa, Xialan Wei, Yongbo Xue, Zhaodi Wu, Zengwei Luo, Ming Xiang,Yonghui Zhang^(*), Guangmin Yao^(*), Neolignans with a Rare 2-Oxaspiro[4.5]deca-6,9-dien-8-one Motif from the Stem Bark of Cinnamomum subavenium., Journal of Natural Products, 2015, 78(7): 1740-1744.

[82]Mengke Zhang, Yangyang Xie, Guanqun Zhan, Liang Lei, Penghua Shu, Yongli Chen, Yongbo Xue, Zengwei Luo, Qian Wan, Guangmin Yao^(*),Yonghui Zhang^(*), Grayanane and leucothane diterpenoids from the leaves of Rhododendron micranthum, Phytochemistry, 2015, 117: 107-115.

[83]Chunmei Chen, Jianping Wang, Junjun Liu, Hucheng Zhu, Bin Sun, Jing Wang, Jinwen Zhang, Zengwei Luo, Guangmin Yao, Yongbo Xue^(*),Yonghui Zhang^(*), Armochaetoglobins A-J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare, Journal of Natural Products, 2015, 78(6): 1193-1201.

[84]Chunmei Chen^(#), Guangzheng Wei^(#), Hucheng Zhu, Yi Guo, Xiao-Nian Li, Jinwen Zhang, Yanfei Liu, Guangmin Yao, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), A new 3,4-seco-oleanane-type triterpenoid with an unusual enedione moiety from Hypericum ascyron, Fitoterapia, 2015, 103: 227-230.

[85]Fuqian Wang, Qingyi Tong, Haoran Ma, Hongfeng Xu, Song Hu, Wei Ma, Yongbo Xue, Junjun Liu, Jianping Wang, Hongping Song, Jinwen Zhang^(*), Geng Zhang^(*),Yonghui Zhang^(*), Indole diketopiperazines from endophytic Chaetomium sp 88194 induce breast cancer cell apoptotic death, Scientific Reports, 2015, 5: 9294.

[86]Tao Zheng^(#), Xiaoyan Yang^(#), Dan Wu, Shasha Xing, Fang Bian, Wenjing Li, Jiangyang Chi, Xiangli Bai, Guangjie Wu, Xiaoqian Chen,Yonghui Zhang^(*), Si Jin^(*), Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway, British Journal of Pharmacology, 2015, 172: 3284-3301.

[87]Chunmei Chen^(#), Hucheng Zhu^(#), Jianping Wang, Jing Yang, Xiao-Nian Li, Jing Wang, Keliang Chen, Yanyan Wang, Zengwei Luo, Guangmin Yao, Yongbo Xue^(*),Yonghui Zhang^(*), Armochaetoglobins K–R, Anti-HIV Pyrrole-based Cytochalasans from Chaetomium Globosum TW1-1, European Journal of Organic Chemistry, 2015, 2015: 3086-3094.

[88]Dongyan Li, Hucheng Zhu, Changxing Qi, Yongbo Xue^(*), Guangmin Yao, Zengwei Luo, Jianping Wang, Jinwen Zhang, Guang Du^(*),Yonghui Zhang^(*), Two new adamantyl-like polyprenylated acylphloroglucinols from Hypericum attenuatum choisy, Tetrahedron Letters, 2015, 56(15): 1953-1955.

[89]Hucheng Zhu^(#), Chunmei Chen^(#), Junjun Liu, Bin Sun, Guangzheng Wei, Yan Li, Jinwen Zhang, Guangmin Yao, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), Hyperascyrones A–H, polyprenylated spirocyclic acylphloroglucinol derivatives from Hypericum ascyron Linn., Phytochemistry, 2015, 115: 222-230.

[90]Hucheng Zhu^(#), Chunmei Chen^(#), Jianping Wang, Xiao-Nian Li, Guangzheng Wei, Yi Guo, Guangmin Yao, Zengwei Luo, Jinwen Zhang, Yongbo Xue^(*),Yonghui Zhang^(*), Penicamedine A, a Highly Oxygenated Hexacyclic Indole Alkaloid from Penicillium camemberti., Chemistry and Biodiversity, 2015, 12(10): 1547-1553.

[91]Qi Ye^(#), Guangmin Yao^(#), Mengke Zhang, Guoli Guo, Yufeng Hu, Jue Jiang, Ling Cheng, Jianguo Shi, Hua Li,Yonghui Zhang^(*), Liu, Hudan^(*), A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling, Carcinogenesis, 2015, 36(3): 318-326.

[92]Ming Yuan, Li Chen, Junwei Wang, Shenjie Chen, Kongchao Wang, Yongbo Xue, Guangmin Yao, Zengwei Luo^(*),Yonghui Zhang^(*), Transition-Metal-Free Synthesis of Phenanthridinones from Biaryl-2-oxamic Acid under Radical Conditions, Organic Letters, 2015, 17(2): 346-349.

[93]Chunmei Chen^(#), Hucheng Zhu^(#), Xiao-Nian Li, Jing Yang, JianpingWang, Gentao Li, Yan Li, Qingyi Tong, Guangmin Yao, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), Armochaeglobines A and B, Two New Indole-Based Alkaloids from the Arthropod-Derived Fungus Chaetomium globosum, Organic Letters, 2015, 17(3): 644-647.

[94]Dongyan Li^(#), Yongbo Xue^(#), Hucheng Zhu, Yan Li, Bin Sun, Junjun Liu, Guangmin Yao, Jinwen Zhang, Guang Du^(*),Yonghui Zhang^(*), Hyperattenins A-I, bioactive polyprenylated acylphloroglucinols from Hypericum attenuatum Choisy, RSC Advances, 2015, 5(7): 5277-5287.

[95]Yanyan Wang^(#), Weiguang Sun^(#), Laxia Chen, Xin Xu, Yunxia Wu, Jinwen Zhang,Yonghui Zhang^(*), Anti-arthritic activity of Fu-Fang-Lu-Jiao-Shuang on collagen-induced arthritis in Balb/c mice and its underlying mechanisms., Pharmacognosy Magazine, 2015, 11(42): 242-249.

[96]Hucheng Zhu, Chunmei Chen, Jing Yang, Xiao-Nian Li, Junjun Liu, Bin Sun, Sheng-Xiong Huang, Dongyan Li, Guangmin Yao, Zengwei Luo, Yan Li, Jinwen Zhang, Yongbo Xue^(*),Yonghui Zhang^(*), Bioactive Acylphloroglucinols with Adamantyl Skeleton from Hypericum Sampsonii, Organic Letters, 2014, 16(24): 6322-6325.

[97]Shasha Xing^(#), Xiaoyan Yang^(#), Wenjing Li, Fang Bian, Dan Wu, Jiangyang Chi, Gao Xu,Yonghui Zhang, Si Jin^(*), Salidroside Stimulates Mitochondrial Biogenesis and Protects against H2O2-Induced Endothelial Dysfunction, Oxidative Medicine and Cellular Longevity, 2014, 2014: 904834.

[98]Youzhi Zhang^(#), Xiaoyan Yang^(#), Fang Bian, Pinhui Wu, Shasha Xing, Gao Xu, Wenjing Li, Jiangyang Chi, Changhan Ouyang, Tao Zheng, Dan Wu,Yonghui Zhang, Yongsheng Li, Si Jin^(*), TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: Crosstalk between NF-κB and PPAR-γ, Journal of Molecular and Cellular Cardiology, 2014, 72: 85-94.

[99]Fang Bian^(#), Xiaoyan Yang^(#), Fan Zhou, Pin-Hui Wu, Shasha Xing, Gao Xu, Wenjing Li, Jiangyang Chi, Changhan Ouyang,Yonghui Zhang, Bin Xiong, Yongsheng Li, Tao Zheng, Dan Wu, Xiaoqian Chen, Si Jin^(*), C-reactive protein promotes atherosclerosis by increasing LDL transcytosis across endothelial cells, British Journal of Pharmacology, 2014, 171(10): 2671-2684.

[100]Ying Tang, Yong-bo Xue, Lei Zhou, Jin-wen Zhang, Guang-min Yao, Zeng-wei Luo, Guang Du^(*), Yong-hui Zhang^(*), New Norclerodane Diterpenoids from the Tubers of Dioscorea bulbifera, Chemical & Pharmaceutical Bulletin, 2014, 62(7): 719-724.

[101]Yang Zhang^(#), Yihong Xia^(#), Yongji Lai, Fang Tang, Zengwei Luo, Yongbo Xue, Guangmin Yao,Yonghui Zhang, Jinwen Zhang^(*), Efficient Synthesis of Kinsenoside and Goodyeroside A by a Chemo-Enzymatic Approach, Molecules, 2014, 19(10): 16950-16958.

[102]Yongbo Xue^(*), Ye Wu, Hucheng Zhu, Xiao-Nian Li, Jin-Fu Qian, Yongji Lai, Chunmei Chen, Guangmin Yao, Zengwei Luo, Yan Li,Yonghui Zhang^(*), Salviprzols A and B, C21- and C22-terpenoids from the roots of Salvia przewalskii Maxim, Fitoterapia, 2014, 99: 204-210.

[103]Junfen Zeng^(#), Yongbo Xue^(#), Yongji Lai, Guangmin Yao, Zengwei Luo,Yonghui Zhang, Jinwen Zhang^(*), A New Phenolic Glycoside from the Barks of Cinnamomum cassia, Molecules, 2014, 19(10): 17727-17734.

[104]Guoli Guo^(#), Guangmin Yao^(#), Guanqun Zhan, Yufeng Hu, Ming Yue, Ling Cheng, Yaping Liu, Qi Ye, Guoliang Qing,Yonghui Zhang^(*), Hudan Liu^(*), N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation, Toxicology and Applied Pharmacology, 2014, 280(3): 475-483.

[105]Zheng-Xi Hu^(#), Yong-Bo Xue^(#), Xiao-Bin Bi, Jin-Wen Zhang, Zeng-Wei Luo, Xiao-Nian Li, Guang-Min Yao, Jian-Ping Wang^(*),Yong-Hui Zhang^(*), Five New Secondary Metabolites Produced by a Marine-Associated Fungus, Daldinia eschscholzii, Marine Drugs, 2014, 12(11): 5563-5575.

[106]Zhengxi Hu, Jianping Wang, Xiaobin Bi, Jinwen Zhang, Yongbo Xue^(*), Yingda Yang, Zengwei Luo, Guangmin Yao,Yonghui Zhang^(*), Colletotrichumine A, a novel indole-pyrazine alkaloid with an unprecedented C16N3-type skeleton from cultures of Colletotrichum capsici, Tetrahedron Letters, 2014, 55(44): 6093-6095.

[107]Junfen Zeng, Yongbo Xue, Penghua Shu, Huiqin Qian, Rongjian Sa, Ming Xiang, Xiao-Nian Li, Zengwei Luo, Guangmin Yao^(*),Yonghui Zhang^(*), Diterpenoids with Immunosuppressive Activities from Cinnamomum cassia, Journal of Natural Products, 2014, 77(8): 1948-1954.

[108]Zhengxi Hu, Yongji Lai, Jinwen Zhang, Ye Wu, Zengwei Luo, Guangmin Yao, Yongbo Xue^(*),Yonghui Zhang^(*), Phytochemical and chemotaxonomic studies on Phyllanthus urinaria, Biochemical Systematics and Ecology, 2014, 56: 60-64.

[109]Hucheng Zhu^(#), Lijun Huan^(#), Chunmei Chen, Jing Yang, Jiangbo He, Yong Chen, Guangmin Yao, Zengwei Luo, Yongbo Xue^(*),Yonghui Zhang^(*), A pair of unprecedented cyclohexylethanoid enantiomers containing unusual trioxabicyclo[4.2.1]nonane ring from Clerodendrum bungei, Tetrahedron Letters, 2014, 55(14): 2277-2279.

[110]Fuqian Wang^(#), Shishi Han^(#), Song Hu, Yongbo Xue, Jianping Wang, Hongfeng Xu, Lu Chen, Geng Zhang^(*),Yonghui Zhang^(*), Two New Secondary Metabolites from Xylaria sp. cfcc 87468, Molecules, 2014, 19(1): 1250-1257.

[111]Yingda Yang, Zhengxi Hu, Zengwei Luo, Yongbo Xue, Guangmin Yao, Yanyan Wang^(*),Yonghui Zhang^(*), A New Sesquilignan Glucoside from Uraria sinensis, Molecules, 2014, 19(1): 1178-1188.

[112]Heng Zheng, Qiong Chen, Menke Zhang, Yongji Lai, Liang Lei, Penghua Shu, Jinwen Zhang, Yongbo Xue, Zengwei Luo, Yan Li, Guangmin Yao^(*),Yonghui Zhang^(*), Cytotoxic ent-Kaurane Diterpenoids from Salvia cavaleriei, Journal of Natural Products, 2013, 76(12): 2253-2262.

[113]Chunmei Chen, Hucheng Zhu, De Zhao, Jun Deng^(*),Yonghui Zhang^(*), Two New Lignans from Phryma leptostachya L., Helvetica Chimica Acta, 2013, 96(7): 1392-1396.

[114]Yongji Lai^(#), Yongbo Xue^(#), Mengke Zhang, Jinwen Zhang, Wei Tang, Junjun Liu, Liang Lei, Juming Yan, Zengwei Luo, Jianping Zuo, Yan Li, Guangmin Yao^(*),Yonghui Zhang^(*), Scapiformolactones A–I: Germacrane sesquiterpenoids with an unusual Δ3-15,6-lactone moiety from Salvia scapiformis, Phytochemistry, 2013, 96: 378-388.

[115]Zhengxi Hu, Yongbo Xue, Guangmin Yao, Zengwei Luo, Yanyan Wang^(*),Yonghui Zhang^(*), Chemical constituents from the leaves of Premna microphylla Turcz, Journal of Chinese Pharmaceutical Sciences, 2013, 22(5): 431-434.

[116]Xincai Hao^(#), Jinwen Zhang^(#), Guanqun Zhan, Yongbo Xue, Zengwei Luo, Guangmin Yao^(*),Yonghui Zhang^(*), Chemical constituents from Teucrium viscidum, Biochemical Systematics and Ecology, 2013, 51: 78-82.

[117]Yongji Lai^(#), Shuiping Ding^(#), Huiqin Qian, Jinwen Zhang, Yongbo Xue, Zengwei Luo, Guangmin Yao^(*),Yonghui Zhang^(*), A New Lignan Glucoside from the Whole Plants of Salvia Scapiformis, Molecules, 2013, 18(9): 11377-11383.

[118]Penghua Shu, Xialan Wei, Yongho Xue, Weijie Li, Jinwen Zhang, Ming Xiang, Mengke Zhang, Zengwei Luo, Yan Li, Guangmin Yao^(*),Yonghui Zhang^(*), Wilsonols A-L, Megastigmane Sesquiterpenoids from the Leaves of Cinnamomum wilsonii, Journal of Natural Products, 2013, 76(7): 1303-1312.

[119]Mengke Zhang, Yan Zhu, Guanqun Zhan, Penghua Shu, Rongjian Sa, Liang Lei, Ming Xiang, Yongbo Xue, Zengwei Luo, Qian Wan, Guangmin Yao^(*),Yonghui Zhang^(*), Micranthanone A, a New Diterpene with an Unprecedented Carbon Skeleton from Rhododendron micranthum, Organic Letters, 2013, 15(12): 3094-3097.

[120]Xialan Wei, Penghua Shu, Tingting Liu, Ming Xiang, Jinwen Zhang, Yongbo Xue, Zengwei Luo, Guangmin Yao^(*),Yonghui Zhang^(*), Steroids and Phenylpropanoids with Immunomodulatory Activities from the Stem Barks of Cinnamomum wilsonii, Chinese Journal of Organic Chemistry, 2013, 33(6): 1273-1278.

[121]Xincai Hao^(#), Jinwen Zhang^(#), Guangxin Xia, Yongbo Xue, Zengwei Luo, Yanyan Si, Guangmin Yao^(*),Yonghui Zhang^(*), A New Triterpenoid from Teucrium viscidum, Molecules, 2013, 18(1): 1262-1269.

[122]Zengwei Luo, Bo Yang, Cheng Zhong, Fang Tang, Ming Yuan, Yongbo Xue, Guanmin Yao, Jinwen Zhang^(*),Yonghui Zhang^(*), A dual-channel probe for selective fluoride determination and application in live cell imaging, Dyes and Pigments, 2013, 97(1): 52-57.