工作经历
2011.11-华中科技大学同济药学院中药与天然药物系,副教授,硕士研究生导师
2012.8-2013.8 UIC/NIH Center for Botanical Dietary Supplements Research访问学者
2006.7-2011.10华中科技大学同济药学院中药系,讲师
教育背景
2018.7-2018.8美国University of California, Los Angeles(SC教学法培训)
2017.6-2017.8英国The University of Manchester(SC教学法培训)
2003.9-2006.7天津大学药学院博士
2000.9-2003.7湖北中医学院中药系硕士
1996.9-2000.7湖北中医学院中药系学士
研究方向
1.中药等民族药活性物质基础及作用机制
2.中药等民族药质量控制新方法
讲授课程
本科生-生药学、分子生药学、药用植物学野外实习、国际传统药物与天然药物
留学生-生药学
研究生-分子生药学
学术兼职
《中草药》青年编委(2019.10-2021.10)
Chinese Herbal Medicines(CHM,中草药英文版)青年编委(2019.10-2021.10)
中国民族医药学会药用资源分会常务理事(2019-);
中华中医药学会中药鉴定分会委员(2019-2023);
武汉市中医药学会中药专业委员会委员(2018-)
主持课题
1.维药寒喘祖帕颗粒治疗激素抵抗性哮喘的初步药效学与作用机制【新疆维吾尔药业有限责任公司,2019.12-2021.12】
2.香血藤等11种药材及饮片湖北省标准研究【湖北省食品药品监督检验研究院,2015.1-2016.12】
3.香血藤生物活性成分及作用机制研究【波谱与原子分子物理国家重点实验室开放课题(T152602),2016.9-2018.9】
4.基于PUF-MS的黑种草子中Keap 1抑制剂的快速发现【华中科技大学自主创新基金, 2016YXMS145,2016.1-2018.12】
5.药用植物香血藤调控NF-кB治疗类风湿关节炎的活性成分研究【国家自然科学基金,NO.31000150,2011.1-2013.12】
国际会议
Jinbo Fang, Dejan Nikolić, Shao-Nong Chen, Rene F. Ramos Alvarenga, David C Lankin, Guido F. Pauli, and Richard B. van Breemen, Structure Determination of 8-Prenylnaringenin Glucuronides Formed by Human Liver Microsomes(Abstracts),Planta Medica,2013,79(10):887, 2013 Annual Meeting of The American Society of Pharmacognosy, St Louis, Missouri, United States, July 14 – 17.
教材及专著编写
1.《中药生物技术》(人民卫生出版社,国家卫健委“十三五”中药专业规划教材)编委。
2.《生药学》(人民卫生出版社,第7版,纸质版和数字教材)编委。
3.《生药学学习辅导与习题集》(人民卫生出版社)副主编。
4.中国毒性民族药志-(科学出版社,上.下卷)编委。
学术论文
1.Jin-Bo Fang, Dejan Nikolić, David C Lankin, Charlotte Simmler, Shao-Nong Chen, Rene F. Ramos Alvarenga, Yang Liu, Guido F. Pauli, and Richard B. van Breemen*,Formation of (2R)- and (2S)-8-Prenylnaringenin Glucuronides by Human UDP-Glucuronosyltransferases,Journal of Agricultural and Food Chemistry,2019,67(42): 11650-11656.
2.Dan Liu, Qiang Yin, Qihua Zhang, Jin Xiang, Changlei Ruan, Huili Liu, Bo Li, Weiliang Zhu, Chun-ping Yin*,Jinbo Fang*, New NO production inhibitors fromHyssopus cuspidatusin LPS-induced RAW264.7 cells,Phytochemistry Letters, 2019, 34: 91-95.
3.Jing Nie1, Ling Xiao1, Lamei Zheng1, Zhifeng Du1, Dan Liu, Jiewen Zhou, Jin Xiang, Junjie Hou, Xiaogang Wang,Jinbo Fang*, An integration of UPLC-DAD/ESI-Q-TOF MS, GC-MS and PCA analysis for quality evaluation and identification of cultivars of Chrysanthemi Flos (Juhua),Phytomedicine, 2019,59(NO. 152803)
4.刘丹,朱小涛,向槿,阮长磊,尹春萍,刘惠丽,徐英黔,胡君一,尹强*,方进波*,神香草倍半萜类化学成分研究,中草药,2019, 50(5): 1049-1054.
5.Yong-qin ZHOU, Xiu-fang WENG,, Rui DOU, Xiao-sheng TAN, Tian-tian ZHANG,Jin-bo FANG*,Xiong-wen WU*, Betulin fromHedyotis hedyotideaameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice,Acta Pharmacologica Sinica,2017, 38(2):201-210.
6.Yan Xiang, Tiantian Zhang, Chunpin Yin, Jiewen Zhou, Rong Huang, Shasha Gao, Lamei Zheng,Xiaogang Wang, Anne Manyande, Xuebi Tian, Jiachun Chen,Jinbo Fang*, Effects of the stem extracts of Schisandra glaucescens Diels on collagen-induced arthritis in Balb/c mice,Journal of Ethnopharmacology, 2016,194:1078-1086.
7.周杰文,杜金龙,侯宪峰,郑腊梅,刘丹,刘惠丽*,王杰,胡君一,徐英黔,陈家春,方进波*,翼梗五味子藤茎倍半萜类化学成分研究,中国中药杂志,2016,41(16):3049-3054.
8.张甜甜,高莎莎,侯俊杰,周永芹,周杰文,王小刚,秦楠,陈家春,段宏泉,方进波*,牛白藤的化学成分及其免疫抑制活性研究,中国中药杂志,2015,40(12):2357-2362.
9.Pei-Pei Zhang, Sha-Sha Gao, Tian-Tian Zhang,Xiao-Gang Wang,Guo-liang Qing,Hong-Liang Jiang, Jia-Chun Chen, Hong-Quan Duan andJin-Bo Fang*.Two new compounds fromSchisandra glaucescens,Journal of Asian Natural Products Research, 2013, 15(5):466-472.
10.张培培,高莎莎,张甜甜,陈家春,段宏泉,方进波*.香血藤中倍半萜类化学成分的研究,中国中药杂志, 2012, 37(22): 3426-3429.
11.刘婷婷,周伟,方进波,叶茂,丁茜,叶小春,陈家春.顶空气相色谱法测定3种中药提取物中有机溶剂残留量,中国医院药学杂志, 2012, 32(4): 290-292.
12.王小刚,方进波,鄢佳,陈家春.分子生药学开放性实验教学的探索与实践,中国中药杂志, 2011, 36(3):383-386.
13.Jinbo Fang, Jiachun Chen, and Hong-Quan Duan.Two New Flavan-4-ol Glycosides fromAbacopteris penangiana,Journal of Asian Natural Products Research, 2010,12(5):355-359.
14.L.-Y. Tian, X. Bai, X.-H. Chen,Jinbo Fang, S.-H. Liu and J.-C. Chen.Anti-diabetic effect of methylswertianin and bellidifolin fromSwertia puniceaHemsl. and its potential mechanism,Phytomedicine, 2010, 17(7):533-539.
15.方进波,陈家春,段宏泉.披针新月蕨细胞毒活性成分研究.中草药, 2010, 41(10):1601-1604.
16.田鸾鸢,陈家春,白雪,方进波.紫红獐牙菜口山酮及环烯醚萜类化合物的研究,天然产物研究与开发, 2010, 22: 979-983.
17.Jinbo Fang, Zhi Yao, Jia-Chun Chen, Yan-Wen Liu, Yoshihisa Takaishi, Hong-Quan Duan.Cytotoxic triterpene saponins fromAlternanthera philoxeroides,Journal of Asian Natural Products Research, 2009,11(3): 261-266.
18.方进波,陈家春,刘焱文,段宏泉.空心莲子草化学成分及抗癌活性研究,中国中药杂志, 2009, 34(19):35-38.
19.Xianghong Chen, Xue Bai, Yihui Liu, Luanyuan Tian, Jianqiu Zhou, Qun Zhou,Jinbo Fang, Jiachun Chen.Anti-diabetic effects of water extract and crude polysaccharides from tuberous root ofLiriope spicatavar. prolifera in mice,Journal of Ethnopharmacology, 2009, 122(2): 205-209,.
20.Xue Bai, Xianghong Chen, Yihui Liu, Luanyuan Tian, Qun Zhou, Shenghong Liu,Jinbo Fang, Jiachun Chen.Effects of water extract and crude polysaccharides fromLiriope spicatavar. prolifera on InsR/IRS-1/PI3K pathway and glucose metabolism in mice,Journal of Ethnopharmacology, 2009, 125(3): 482-486.
21.Tian Luan Yuan, Jia Chun Chen,Jinbo Fang. A new monosaccharide fromSwertia puniceaHemsl.,Chinese Chemical Letters, 2009, 20(6) :684-686.
22.Xianghong Chen, Yihui Liu, Xue Bai, Li Wen,Jinbo Fang, Mao Ye and Jiachun Chen.Hypoglycemic Polysaccharides from the Tuberous Root ofLiriope spicata,Journal of Natural Products, 2009, 72 (11): 1988-1992,.
23.Tian Luan-Yuan, CHEN Jia-Chun, HUANG Feng-Jiao&FANG Jin-Bo, Simultaneous Determination of Four Active Components inSwertiaby RP-HPLC,Chinese Journal of Natural Medicines, 2008, 6(6):444-449.
24.Jinbo Fang, Wei Jia, Wen-Yuan Gao, Zhi Yao, Jie Teng, Ai-Hua Zhao, Hong-Quan Duan.Antitumor constituents fromAlternanthera philoxeroides,Journal of Asian Natural Products Research, 2007, 9(6-8): 511-515.
25.方进波,刘焱文,张彦文,滕杰,段宏泉,空心莲子草抗病毒活性成分研究,中草药, 2007, 38 (7) : 976-979.
26.方进波,段宏泉,张彦文,高石喜久,空心莲子草的化学成分研究,中国中药杂志, 2006, 31(13) :1072-1075.
奖励
2011年获华中科技大学教学质量优秀奖二等奖
2010年获华中科技大学青年教师讲课比赛三等奖
专利
1.方进波,叶茂,陈家春,吴宇星。一种治疗慢性盆腔炎的药物及其制备方法,(申请号CN201110107353.8, 2011.04.26,公开号: CN102362949B,2014.01.22)